Anti-inflammatory and Antioxidant Properties of Herbal Extracts: Mechanism and Therapeutic Potential
Keywords:
Herbal extracts, Anti-oxidants, Bioactive components, Inflammation, NanoparticlesAbstract
Bioactive compounds mostly with potent anti-inflammatory and antioxidant properties that found in herbal extracts, have acknowledged for their various medicinal benefits. Herbal extracts have the ability to suppress pro-inflammatory cytokine, and abundant in bioactive substances like flavonoids, polyphenols, terpenoids, and alkaloids, fight inflammation and oxidative stress in one of the two important elements in the etiology of chronic liver diseases like alcoholic liver disease and non-alcoholic fatty liver disease. Cellular damage results from oxidative stress brought on by drugs, alcohol, and environmental contaminants that throw off the equilibrium of important enzymes like superoxide dismutase, glutathione, and catalase. In addition to restoring these enzymes function, herbal antioxidants also lessen inflammation and lipid peroxidation. In both acute and chronic states, several substances, including curcumin, betaine, and l-theanine, exhibit hepatoprotective properties. Potentially useful anti-inflammatory and antioxidant properties of herbal extracts could pave the way for plant-based, natural remedies for the management and prevention of chronic diseases. Bioactive substances, like carotenoids and polyphenols, have demonstrated anti-atherosclerosis, cancer prevention, and rejuvenation properties. Various compounds and chemicals contribute to synthetic antioxidants and enhance the production of functional foods with potential medicinal uses. Furthermore, the solubility, bioavailability, and therapeutic potential of herbal extracts greatly increased when they are included into nanoparticle delivery systems. This collaboration between technology and nature creates new, less harmful treatment options for inflammatory and oxidative diseases. The use of these phytomedicines' therapeutic potential in a better way, more studies and standardization are required.
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